AZD6738
AZD6738 is a potent inhibitor of ATR kinase. It potentiates the cytotoxicity of cisplatin and gemcitabine in non-small cell lung cancer (NSCLC) cell lines with intact ATM kinase signaling, and potently synergizes with cisplatin in ATM-deficient NSCLC cells.
Product Name:
AZD6738
>Also Known As:
4-[4-[1-[[S(R)]-S-methylsulfonimidoyl]cyclopropyl]-6-[(3R)-3-methyl-4-morpholinyl]-2-pyrimidinyl]-1H-pyrrolo[2,3-b]pyridine
>Catalog No.:
F8140
>Size:
5 mg
>CAS:
1352226-88-0
>Formula:
C20H24N6O2S
>Molecular Weight:
412.51 Da
>Form:
Lyophilized powder
>Quality Assurance:
>98% by HPLC and NMR
>Source:
Synthetic
>Storage:
Eligible for room temperature shipping. Store at -80°C upon receiving
>PDF Data Sheet:
Download PDF datasheet
>Image(s):
N/A
>Shipping Method:
Room temperature shipping
>References:
Vendetti FP, et al. (2015) Oncotarget. Oct 27. THZ1-R 18482018
