6xHis-ISG15
Interferon – stimulated gene 15 (Isg15) is a 15 kDa Ub – like protein. It is linked to proteins in much the same way as Ub, using the E1, E2, E3 cascade. U bE1L and UbcH8 are the specific E1 and E2, respectively, to mediate protein ISGylation. Several E3s have also been found. Isg15 is induced by type I interferons (IFNα/β) and bacterial and viral infections. Studies are still being conducted to discover the biological functions of Isg15.
Product Name:
6xHis-ISG15
>Also Known As:
G1P2; IP17; UCRP; IFI15; hUCRP
>Catalog No.:
E2100
>Size:
500 µg
>Molecular Weight:
17.9 kDa
>Species:
Human
>Source:
Bacterial recombinant
>Stock:
20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol
>Concentration:
See tube label
>Quality Assurance:
~95% by SDS-PAGE, see datasheet for gel image
>Storage:
Store at -80°C; avoid multiple freeze-thaw cycles
>PDF Data Sheet:
PDF Datasheet， MSDS
>NCBI RefSeq:
NM_005101
>Image(s):
N/A
>Shipping Method:
Dry ice shipping
>References:
1. D’Cunha J, et al. (1996) Proc Natl Acad Sci USA 93(1), 211 – 215.
2. D’Cunha J, et al. (1996) J Immunol 157(9), 4100 – 4108.
3. Zhang D, et al. (2011) J Interferon Cytokine Res 21 (1), 119 – 130. CH5424802 18477923
